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iCast covered stent system

iCast covered stents have the first to market balloon expandable, fully encapsulated stent design that has served physicians with more than 850,000 units sold.  Known for its precision and predictability — the versatile iCast covered stent has been meeting the needs of surgeons and patients for 20 years, and is the only durable solution backed by decades of real-world evidence. [2][3] 

Indication:

The iCast covered stent system is indicated for improving luminal diameter in patients with symptomatic atherosclerotic disease of the native common and/or external iliac arteries up to 110 mm in length, with a reference vessel diameter of 5 to 10 mm.

The iCast covered stent system is not available outside of the United States.

 

 

Bilateral common iliac restenosis remodeled with the iCast covered stent system 

The predictability and precision you need for covered stent placement. [1] [2]

Versatility to adapt to different treatment needs, with flexibility to conform to the anatomy. [1] [2] [6] [7] [8]

Predictable and Precise[2]

  • Low profile, reliable stent retention force and secure trackability facilitate stent implantation[2]
  • Designed for secure delivery and placement: average stent securement force is 2-4 times higher than peak insertion forces[2]
  • 6 and 7 French compatible[2]
  • Radiopaque markers enhance visibility during deployment and assist with accurate stent placement.[1]
  • Designed for pushability and trackability through tortuous anatomy with conformance to iliac arteries [1]
  • Predictable recoil and foreshortening promotes precise deployment [2]

Please see the iCast order information found in the documents tab for detailed compatibility. 

Refer to Instructions for Use for current indications, warnings, contraindications, and precautions. 

Group of stents

Versatile and Flexible[2]

  • Full encapsulation with ePTFE helps mitigate the risks related to vessel perforation. [6] [9]
  • Smooth inner lumen offers ease of navigation during re-intervention. [2]
  • Able to post-dilate and flare stent: conforming to the anatomy and customizing each patient's treatment [1][8]
  • 316L stainless steel struts provide additional radial force - designed to support stent patency.[1]
  • Dog-bone inflation design is intended to reduce the chances of embolization [7]
  • Stent structure, cell design, and system provide versatility and flexibility in delivery and placement.[2]

Optimized patient outcomes today, tomorrow and into the future [1][4][5]

  • iCast is the only balloon-expandable covered stent with real-world data spanning decades, including a reported 5-year primary patency rate of 74.7%. [2][3]
  • Proven two-fold lower reintervention compared to bare metal stents at 5 years post-procedure.[1]

COBEST -   5 year results: iCast vs. Bare Metal Stent [1]

Systematic review of covered balloon-expandable stents for treating aortoiliac occlusive disease [3]

  • The iCast/Advanta V12 balloon-expandable covered stent has long-term, real-world follow-up, including a reported 5-year primary patency rate of 74.7%.

  • The iCast/Advanta V12 was the most common device studied in the literature from 2000-2019 (10/15 publications; 66.7%).

  • The iCast/Advanta V12 studies treated patients with more severe disease (a greater number of TASC C&D lesions) and more severe symptoms (more Rutherford classification 4 & 5) compared to patients enrolled in clinical trials studying other covered balloon-expandable stents.

  • Freedom from TLR:  Results were comparable for all covered balloon-expandable stents at 1 year.  The iCast/Advanta V12 has long-term target lesion revascularization data.

iCARUS: Single-Arm IDE study with 3-year follow-up[4]

iCarus 3years study results

Freedom from Target Lesion Revascularization (TLR)​

  • Real-world patient population with multiple lesions and bilateral disease​
  • Study showed sustained clinical benefit with freedom from target lesion revascularization (TLR) up to 3 years 

Pre and post images from occlusive disease treatment with iCast covered stent system

 

Bilateral illiac artery occlusion

Bilateral Iliac artery occlusion - pre restoration

Pre treatment

Bilateral Iliac artery occlusion - post restoration

Post treatment

Restoration of the lumen diameter with iCast covered stent in RIA. iCast covered stents overlapped in LIA.

RIA: Right iliac artery
LIA: Left iliac artery

Bilateral common iliac artery occlusion

Bilateral Common Iliac artery occlusion - pre restoration

Pre treatment

Bilateral Common Iliac artery occlusion - post restoration

Post treatment

Restoration of the lumen diameter with iCast covered stents in RIA and LIA.

RIA: Right iliac artery
LIA: Left iliac artery

  1. 1. Mwipatayi, B.P., et al., Durability of the balloon-expandable covered versus bare-metal stents in the Covered versus Balloon Expandable Stent Trial (COBEST) for the treatment of aortoiliac occlusive disease. Journal of Vascular Surgery, 2016

    (Mwipatayi BP, et al. showed less restenosis when comparing Advanta V12 covered stent to bare metal stent in TASC C and D through 5 years.)

    View on PubMed
  2. 2. Both Advanta V12 and iCast covered stent systems are manufactured by Atrium Medical Corporation. Advanta V12 is available outside of the United States. iCast is available only in the United States. Both products are the same physical stent and delivery system under different brands. Duration of use, number of units, and publications are combined Advanta V12 and iCast records. Data on file.

  3. 3. Mwipatayi, B.P., et al., A systematic review of covered balloon-expandable stents for treating aorto-iliac occlusive disease. Journal of Vascular Surgery, 2020.

    View on PubMed
  4. 4. Laird et al., iCAST Balloon-Expandable Covered Stent for Iliac Artery Lesions: 3-Year Results from the iCARUS Multicenter Study. Journal of Vascular and Interventional Radiology, 2019

    View on PubMed
  5. 5. Sabri S, et al., Outcomes of Covered Kissing Stent Placement Compared with Bare Metal Stent Placement in the Treatment of Atherosclerotic Occlusive Disease at the Aortic Bifurcation. Journal of Vascular and Interventional Radiology, 2010

    View on PubMed
  6. 6. Al-Mukhaini et al., Coronary perforation and covered stents: an update and review. The Official Journal of the Gulf Heart Association; Heart Views, 2011

    View on PubMed
  7. 7. Grimme et al., Polytetrafluoroethylene Covered Stent Placement for Focal Occlusive Disease of the Infrarenal Aorta. Eur J Vasc Endovasc Surg, 2014

    View on PubMed
  8. 8. van der Riet et al., Three-Dimensional Geometric Analysis of Balloon-Expandable Covered Stents Improves Classification of Complications after Fenestrated Endovascular Aneurysm Repair. J of Clinical Medicine, 2022

    View on PubMed
  9. 9. Rogers C, et al., Non-GLP study of biologic responses to uncoated and PTFE coated steel stents in rabbit iliac arteries. MIT iCast IH Study, 1997

    View on PubMed